Dr. D. CBD

Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain.
Apr
1
2019

Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain.

Written by Dr D / CBD, Pain
TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons.
Aug
28
2018

TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons.

Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways.
Jul
16
2018

Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways.

Written by Dr D / Neuroscience, Pain
Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors
Jul
16
2018

Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors

Written by Dr D / Neuroscience, Pain
Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort
Jul
16
2018

Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort

An analgesia circuit activated by cannabinoids.
Jul
16
2018

An analgesia circuit activated by cannabinoids.

Written by Dr D / Neuroscience, Pain
Interference with GABA transmission in the rostral ventromedial medulla: disinhibition of off-cells as a central mechanism in nociceptive modulation.
Jul
16
2018

Interference with GABA transmission in the rostral ventromedial medulla: disinhibition of off-cells as a central mechanism in nociceptive modulation.

Written by Dr D / Neuroscience, Pain
Evidence that an excitatory connection between the periaqueductal gray and nucleus raphe magnus mediates stimulation produced analgesia.
Jul
16
2018

Evidence that an excitatory connection between the periaqueductal gray and nucleus raphe magnus mediates stimulation produced analgesia.

Written by Dr D / Neuroscience, Pain
The nonpsychotropic cannabinoid cannabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function.
Jul
10
2018

The nonpsychotropic cannabinoid cannabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function.

Written by Dr D / CBD, Glycine Receptor, Pain
Cannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritis.
May
28
2018

Cannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritis.