Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain. 01 Apr Continue reading →
TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. 28 Aug Continue reading →
Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways. 16 Jul Continue reading →
Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors 16 Jul Continue reading →
Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort 16 Jul Continue reading →
Interference with GABA transmission in the rostral ventromedial medulla: disinhibition of off-cells as a central mechanism in nociceptive modulation. 16 Jul Continue reading →
Evidence that an excitatory connection between the periaqueductal gray and nucleus raphe magnus mediates stimulation produced analgesia. 16 Jul Continue reading →
The nonpsychotropic cannabinoid cannabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function. 10 Jul Continue reading →
Cannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritis. 28 May Continue reading →