Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects. 22 Nov Dr D Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors.